Epigenomic of Aging
نویسندگان
چکیده
منابع مشابه
Detection of Epigenomic Network Community
In this paper we propose network methodology to infer prognostic cancer biomarkers based on the epigenetic pattern DNA methylation. Epigenetic processes such as DNA methylation reflect environmental risk factors, and are increasingly recognised for their fundamental role in diseases such as cancer. DNA methylation is a gene-regulatory pattern, and hence provides a means by which to assess genom...
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Genes occupy only a minor fraction of genomes such as ours; however, histone and nonhistone chromosomal proteins and methylated DNA bases are distributed over both genic and nongenic regions. These widespread "epigenomic" features can be mapped and characterized by alternative applications of the same microarray technologies that have been used for conventional transcriptional profiling. Here w...
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The age of omics is in full swing. Full genome sequences and the use of DNA microarrays to monitor gene expression on a genome-wide scale arrived on the scene a little over a dozen years ago, and today major developments in DNA sequencing technology have ushered in a new era in the study of gene regulation. Around the turn of the century, the introduction of massively parallel next-generation D...
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ژورنال
عنوان ژورنال: Hereditary Genetics
سال: 2013
ISSN: 2161-1041
DOI: 10.4172/2161-1041.1000e106